When to screen and not to screen

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When to screen and not to screen

Colorectal cancer (CRC) is the third most common cause of cancer-related deaths with treatment of advanced and metastatic CRC (mCRC) remaining palliative at best. (1) The epidermal growth factor receptor (EGFR) has been identified as a therapeutic target for a multitude of malignancies, including mCRC. Ligand-binding to EGFR results in the subsequent activation of multiple signal transduction p...

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To screen or not to screen.

All screenings lack efficiency because they rely too often on biaised and underpowered statistics. Healthcare business makes tremendous benefits out of well established and easy profit earning processes from screenings to treatments; therefore patients enlightened consent is under influence. In the wealthiest parts of the world, this field of public health sciences impulses studies with intense...

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Depression: to screen or not to screen?

There are few more difficult diagnoses to make than depression in sick older patients in a general hospital. There is no diagnostic test and confounding physical symptoms, the sheer fact of being ill in the inhospitable and frightening environment of a hospital away from home, possibly for weeks, and still facing an uncertain recovery makes interpretation of symptoms very difficult. When does a...

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Hepatoblastoma: when to screen?

Introduction Hepatoblastoma is a rare hepatic malignancy that is seen in Familial Adenomatous Polyposis (FAP). The occurrence is four hundred fold higher than the general population [1]. Hepatoblastoma is generally treatable with surgery; in addition it is highly responsive to chemotherapy. While the literature reports on this extracolonic manifestation of FAP, no screening recommendations exis...

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ژورنال

عنوان ژورنال: Cancer Biology & Therapy

سال: 2014

ISSN: 1538-4047,1555-8576

DOI: 10.4161/cbt.27741